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Rivaroxaban potently limited prothrombinase exercise [inhibitory concentration 50?% (IC50) Two.1?��?0.4?nM], and also clot-associated Aspect Xa exercise (IC50 75?nM) [19, 20]. Throughout individual plasma, rivaroxaban limited endogenous Aspect Xa exercise within a concentration-dependent way by having an IC50 involving 21?��?1?nM [19]. In the ex lover vivo examine, rivaroxaban in a single serving

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